The human epidermal growth factor receptor (HER) family has four receptors: HER1(EGFR), HER2, HER3 and HER4. These receptors and their associated signaling pathways have been the focus of research and development of targeted therapies.
Biologics such as erlotinib, lapatinib and trastuzumab were developed as a result of this research. Many of these targeted therapies use diagnostic tests to identify the best patients for the treatment.
|Monogram's VeraTag is a proximity-based technology platform designed to detect and quantify proteins and protein-protein complexes, including homodimers and heterodimers of the HER family of cell-surface receptors.|